titus is right about them being nitrate factories if not maintained. that being said i ran a fluval 405 on my 60 gallon and found it to work quite well. it gave good flow in my tank. I used the stock media that came in it though there may be better choices. When i cleaned mine i would clean it using the water i removed from the tank to save anything that was living in my filter. (after a while there was a fair amount in there). If you use fresh water to clean it, don't clean all the media at once. do it in sections. this is how i did mine- week one hit your sponges, week two do your bio balls, week three do your ceramic noodles, week 4 change your carbon.
clean it once a week when you do your water changes, remove any dieatrus(sp) sitting at the bottom of the filter.
Hope this helps
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