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			 Just do the water change after treatment and everything will be fine,i have never heard of any negative effects and we sell alot of it. 
		
	
		
		
		
		
		
	
		
		
	
	
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			#2  
			
			
			
			
			
		 
		
		
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			 I fought Cyano in my nano for ages to no avail.  I tried Chemiclean once about 8 months ago and I haven't seen any cyano since then. Everything in the tank stayed very happy (except the cyano).  Just turn off your skimmer for a day or two as it will overflow like crazy and aerate the tank by some other means. 
		
	
		
		
		
		
			
		
		
		
		
	
		
		
	
	
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