Perhaps my post had more of a confrontational tone in reading than it did in my head while typing, but the statement that protozoans develop resistance in a different manner from bacteria is false.
Case in point: malaria is caused by a Protozoa with a lengthy and complex life cycle. Chloroquine resistance appeared in it independently on 3 different continents in the 1950s. It's practically useless as a malaria medication across broad swaths of the tropics today. By numbers and area, resistance to chloroquine is one of the largest single losses of a useful drug in history.
There's no reason to believe C. irritans protozoans won't exhibit the same degree of adaptability.
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