Prazi-pro in my experience is reef safe. I have used the therapeutic dose many times after adding new fish in a full blown reef with no ill effects.
There are some cautions though. If you are carbon dosing i would not continue. Because prazi pro will cause your skimmer to over flow, it is typically advised to turn it off during treatment. This can drop the oxygen in your tank if you are carbon dosing due to bacterial activity.
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