I've used it in my tank twice now. The first time was probably in the spring or summer and I don't think I used enough of it or for long enough and the cyano came back within a week, but other than that and a skimmer that went crazy for days, there were no other effects.
This most recent time, according to date stamps on posts here, was just about exactly a month ago. This time after the 20% water change at the 48 hour mark, I did a second dose to try and make sure I'd killed it all. Strangely, even though I know it's not supposed to work on them, the dusting of dinos that have waxed and waned on my sand bed for the better part of a year (and I've confirmed their identity under a microscope) utterly vanished. I only let the second treatment go for 24 hours because my elegance coral and one of my frogspawns were starting to look a little worse for wear, so I did the 20% water change, dropped a bag of carbon in my filter sock, and skimmed wet until the skimmer went back to normal (about 3 days). When I did that last water change I tested my phosphate levels and they had jumped from 0.00 on a hanna checker to 0.05.
After that I started an aggressive dosing campaign of MB7 (the tank runs biopellets) and changed the GFO every few days for a couple of weeks.
January 15th and there isn't a trace of the cyano. All corals are doing just fine, though I think I might have driven the nutrients too low.
I know some people say they've nuked their tanks with this stuff, but I've never seen so much as a reaction from anything, other than the widespread death of cyano bacteria.
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