yes you can use a buffing wheel but it must be a new one, or have only been used on acrylic before, try sanding the scratches out by hand with the black wet/dry sandpaper, try 220, 400, 600, 800, 1200...... then work it with a power buffing wheel and the novus scratch remover creams, be careful not to melt the acrylic with the buffing wheel. when sanding out the scratches, you should sand a much larger area then just where the scratch is so the you dont cause very noticable dips and waves in the acrylic, sanding a larger area makes the repaired area less noticable. hope that makes sense....