Design #1 all the way. Not a fan of the up and over look. Doing the notch for design 1 is a pain if you do it yourself and a little more pricey if that glass shop does it. Design 2, if you do the long sides plus the overflow as one piece you are still having to put a notch into the glass. If you don't do it as one piece, you'll have some funky silicone work at the top edge that will be ugly and weak (gap between panels should be 1 mm). I would worry about stress points on the back glass if you do the notch so long as your glass is the right thickness. We over engineer the glass thickness as it is. Just doing a back of the napkin calculation on stress around the notches you're still at a safety factor of 4. I did a notch on my tank, couldn't be happier.
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