Never had a cycle in a fresh water tank just amonnia spikes, cured by 30% water change. Hole in head can take several weeks or months to cure. Best is to move the fish to a very small tank to treat, takes less meds and is more concentrated. Syphon gravel out during water changes until its all out, rinse the new stuf and put it in using a cup close to the bottom of the tank.
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