I used Chemi-clean on a tank a couple months ago, one treatment and it never returned. I first got out as much as I could with a tooth brush and turkey baster, and then applied the Chemi-clean exactly as per instructions, incl changing water 48 hours later. I was prepared to do a 2nd treatment, but it wasn't necessary.
Previously I wrestled for 6 months or more with cyano in this tank, trying everything, and it would always return. But not this time. So the stuff works, I am convinced of that.
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