Ha, with a 300 gal to start with, the world is your oyster, pun intended. I went straight into a marine set up, no fresh water experience, but a few friends/relatives have FW tanks so I know a little about that scenario. IMO the things that are quite a bit different between FW & SW are lighting, flow & water quality in no particular order.
Probably the first thing on the agenda would be water quality, best to get a RODI system & use pure water to mix up your soup with from the outset. No unkowns getting into your system that way.
Next, I'd say flow. Even during the cycle you'll want good water movement, so look into getting some propeller pumps since they are better at moving water in all the nooks & crannies than the laminar flow from conventional powerheads or pumps.
Lighting.... at the start you won't need to worry too much about it. It's going to take some time to cycle that bad boy, so whatever you have now for FW will probably be ok. Then, once you start adding livestock, you can put together a lighting plan. Chances are you're going to add a fish or two first, so again, lighting does not need to be ultra bright for them. As far as coral, good idea to start with some easier softies & LPS, so now you can look at bumping up the light intensity a little. It will probably be a few months before you're to that point, so you'll have plenty of time for additional research. This will be one of the larger expenses for a tank your size, so choose well depending on what your ultimate goal is. LED is definitely poised to edge out the current MH/T5HO technology, but still quite costly. Either way, lights are going to be $$$$$ if you're thinking full reef with an abundance of SPS coral. With 300 gals you can cram a few critters in there. Best of luck.
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