probiotic systems like biopellet or zeovit needs to run the parameter close to nsw which is 7dkh 380-400 cal and 1250-1350 mag. in my own experience as well as several other reefers I talked to who run probiotic systems wether its pellets, zeo or prodibio has encounter issue when dkh jumps above 9, usually alk burn will start to show at the tips and or paleness of the coral tissue, then if dkh goes above 10 stn and rtn will soon follow. When that happens, it become an irreversible domino effect.
Also when running probiotic system, the bacteria stripes potassium out of the water so fast, with the combination of high alk, it will for sure wreck havoc. I use redsea to test my potassium, when I first tested it, it was arond 360ppm since then I've raised it up to 430 using zeo k balance as I found that to be more effective than other products.
Those 2 problems really caused me a lot of headachs in my tank, it caused 3-4 colonies that I had for over a year to die off over the course of couple of days. I did a lot of research finally narrowing it down to those 2 problems. I spent the next week or two lowering my alk and boosting my potassium, it took a bit but everything has finally starting to turn around. It seem that around 7dkh and 430 potassium, even if my calcium is lower everything still seems to be doing well. I had one colony that has been with me from the start that was at the brink of death, I just couldn;t bring myself to toss him out, its now starting to make a slow but steady come back.
if I were you Milad I would give that a try, but remember to go slow. You risk more issues if you drop your alk too fast.