in a fowlr you can get away with out a clean up crew especially if you go bare bottom.besides most of the predators you throw in a 220g are prob going to make a meal out of most of em. go big skimmer the biggest and best your budget will allow, get some grazing fish will also help.if you can run a sump i would recommend doing so and run a fuge for nutrient export it will cut down on any algae you will get.
if its a reef your shooting for then your gonna want to have a CUC its not necessary but will go along way as a tank that big is hard to clean and hard to get around rock and corals .
remember to buy reefsafe fish and for every fish you buy google it and read up on it so you dont buy something you regret which we all have one time or another.
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