It is my personal experience that coral death (by whatever mysterious cause) DOES spread. When one coral dies, there is an increased chance that NEARBY corals will then die.
Maybe you build your system so that it CAN be all connected...but can be also be isolated to run as separate systems in the event of quarantine or concern.
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400 gal reef. Established April, 2007. 3 Sequence Dart, RM12-4 skimmer, 2 x OM4Ways, Yellow Tang, Maroon Clown (pair), Blonde Naso Tang, Vlamingi Tang, Foxface Rabbit, Unicorn Tang, 2 Pakistani Butterflies and a few coral gobies
My Tank: http://www.canreef.com/vbulletin/showthread.php?t=28436
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