Personally, I think substrate looks more natural. the only reason a sand bed can cause problems is if it's not maintained properly. If you do a shallow bed, just siphon it out when you do water changes. No big deal. Also, there are great cleaners like Nasarius Snails that stir the sand bed up.
Even with NO sand bed, you must keep detritus off the bottom glass, so it's pretty much the same.
Do what you think looks best, but research it and make sure you are avoiding potential problems.
Good luck
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