You should be fine to scrub the glass. Be careful though as sometime those type of 'pests' may release spores when agitated and you go from having 10 this month to 100 next month.
As far as critters you can treat it like your regular display tank and add snails and other inverts to keep it clean. Even fish if you wanted! I'd probably try snails first and see how they do. It all really depends how it's setup though. I assume since it's a refuge you already have a light to grow chaeto or some other macroalgaes/pods so it'd be fine for inverts (I'd feel bad if they were always in the dark). Hope that helps!
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