I would only do the top layer not the whole thing 5+ inches is a lot you could have a problem disturbing that much. If you have good flow it should take care of itself. Just clean the top one inch and leave the rest.
That is just my 2 cents though as you know everyone has their own opinion in this hobby. 
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150 Gal system 3'x3' 400W M/H, Bekett skimmer, Dart return,1/4 HP Chiller
180 Gal Drop tank, LED lights, Bubble master 250 skimmer,Hammerhead on a closed loop, Speed wave return.
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