Depends on the type. I think most would agree Fromia sp. and Linckia sp. are safe, most of the other types commonly sold really aren't. I see a lot of those chocolate chip types in local shops, apparently they're a no-no.
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-Quinn
Man, n. ...His chief occupation is extermination of other animals and his own species, which, however, multiplies with such insistent rapidity as to infest the whole habitable earth, and Canada. - A. Bierce, Devil's Dictionary, 1906
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