I also finding this discussion becoming tedious so I think this will be my last contribution. It is truly unfortunate that there are people who continue to hold views in light of evidence to the contrary. A few last comments.
Quote:
Originally Posted by FitoPharmer
i would just like to see more science and studies, and i don't mind looking for them if i'm told where or what to look for.
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This how you do journal research in science. There is a tool called MEDLINE (Medical Literature Analysis and Retrieval System) which allows you to do a search in about 5000 scientific journals.
Searching H1N1 vaccine, I get 1217 journal references for h1n1 vaccine - 46 for the month of October alone. You would then have to go to a university biomedical library to read these articles as they are subscription based and very few are available for free.
Other searches yield about 3500 references for H1N1 and 3000 for H5N1 on which the Arepanrix vaccine was based upon.
Quote:
Originally Posted by FitoPharmer
what problems you have with the side effect portion of GSK's own product fact sheet for the vaccine?
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This are the risks directly from the vaccines' patient information sheet.
Very common (may occur with more than 1 in 10 doses): Pain at the injection site, Headache, Fatigue, Redness or swelling at the injection site, Shivering, Sweating, Aching muscles, joint pain
Common (may occur with up to 1 in 10 doses):Reactions at the injection site such as bruising, itching and warmth, Fever, Swollen lympth nodes, Feeling sick, diarrhea
Uncommon (may occur with up to 1 in 100 doses): Dizziness, Generally feeling unwell, Unusual weakness, Vomiting, stomach pain, uncomfortable feeling in the stomach or belching after eating, ability to sleep, Tingling or numbness of the hands or feet, Shortness of breath, Pain in the chest, Itching, rash, Pain in the back or neck, stiffness in the muscles, muscle spasms, pain in extremity such as leg or hand
Rare (may occur with up to 1 in 1000 doses): Allergic reactions leading to a dangerous decrease of blood pressure, which, if untreated, may lead to shock. Doctors are aware of this possibility and have emergency treatment available for use in such cases, Fits, Severe stabbing or throbbing pain along one or more nerves, Low blood platelet count which can result in bleeding or bruising
Very Rare (may occur with up to 1 in 10,000 doses): Vasculitis (inflammation of the blood vessels which can cause skin rashes, joint pain and kidney problems), Neurological disorders such as encephalomyelitis (inflammation of the central nervous system), neuritis (inflammation of nerves) and a type of paralysis known a Guillain-Barré Syndrome
Most of the side effects are what you would expect with any vaccination - pain, bruising and swelling. I would expect the list of rare side effects is there for legal reasons so someone could not say they were uninformed.
For comparison, here is a list of possible side effects from the information sheet for Alka Seltzer: nausea, vomiting, ringing in ears, diminished hearing, confusion, agitation, lethargy, fever, coma, respiratory alkalosis, metabolic acidosis, convulsions, pulmonary edema, cardiovascular collapse.
One last word on Aspartame. A medline search of 111 references regarding Aspartame toxicity gives us the publicly accessible reference. Note the last line in the abstract - Aspartame is safe!
Crit Rev Toxicol. 2007;37(8):629-727.
Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies.
Magnuson BA, Burdock GA, Doull J, Kroes RM, Marsh GM, Pariza MW, Spencer PS, Waddell WJ, Walker R, Williams GM.
Burdock Group, Washington, DC, USA.
bmagnuso@umd.edu
Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the current consumption levels worldwide, the toxicology, and recent epidemiological studies on aspartame. Current use levels of aspartame, even by high users in special subgroups, remains well below the U.S. Food and Drug Administration and European Food Safety Authority established acceptable daily intake levels of 50 and 40 mg/kg bw/day, respectively. Consumption of large doses of aspartame in a single bolus dose will have an effect on some biochemical parameters, including plasma amino acid levels and brain neurotransmitter levels. The rise in plasma levels of phenylalanine and aspartic acid following administration of aspartame at doses less than or equal to 50 mg/kg bw do not exceed those observed postprandially. Acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs have consistently found no adverse effect of aspartame with doses up to at least 4000 mg/kg bw/day. Critical review of all carcinogenicity studies conducted on aspartame found no credible evidence that aspartame is carcinogenic. The data from the extensive investigations into the possibility of neurotoxic effects of aspartame, in general, do not support the hypothesis that aspartame in the human diet will affect nervous system function, learning or behavior. Epidemiological studies on aspartame include several case-control studies and one well-conducted prospective epidemiological study with a large cohort, in which the consumption of aspartame was measured. The studies provide no evidence to support an association between aspartame and cancer in any tissue. The weight of existing evidence is that aspartame is safe at current levels of consumption as a nonnutritive sweetener.