You said you tank was ok for the first year then started to go south? Improves after a water change for a short while? Mabey look at the possibility that something has built up in your tank to toxic levels. Are you skimming enough, do you have enough LR, running phosban, what shape is your sand bed, running a Fuge? All valid questions that should be looked at also. Look also for things like stray voltage, some foreign metal object in the tank, something you started dosing. I find it odd that parameters that are slightly off would cause so much trouble. Especially if your levels were the same during the first year.
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