I guess everyone's situation is different. My tank is 5 years old with a 2-3 inch sandbed and I never touch it. I have narcisse snails (probably about 10) and a sand sifting starfish. Recently I had to replace my tank and was told that I should probably put in a new sandbed which I did. Much to my surprise, the old sandbed looked as white and clean as the day I put it in with no odor other than that of a beach. There were no green or black patches. I was surprised and thought that I probably should have just kept the old one but so far so good.
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65 g mixed fish with various lps, 50 lbs live rock, remora skimmer, 2 A150W sky blue Kessils
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