You should not have a problem if you run perpendicular to the floor joists and close to main beam that support the joists. I have a 150gal. DT and 50gal. sump under the stand. Dim. of stand is 48" x 30" with a soild base (plywood) which sitting on 4 floor joists 2 x 10. Before I started to fill it I had a plumb bob hanging from the joists in the basement so I can check if the floor was bending due to the weight of the tank. It"s been over a year now with no problems.
Hopes this helps.
Ed.
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