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Wilipedia
Frequency (Hz) Frequency is generally not a problem - most travel items will work OK on either 50 or 60 Hz. If all the electrical appliance does is produce heat and/or light, then the frequency is unlikely to matter.
Frequency is most likely to affect clocks and devices with motors. They may run faster or slower than they should and may be damaged in the long run as a result. Again, though, some motorised devices may function correctly on either 50 or 60 Hz - especially if they also operate on batteries. Just look on the label or plug.
However, you still may need to be careful if you have a sensitive and/or expensive device that converts AC (power from the wall) into DC (battery-like current) - especially if you also need to convert the voltage. A device will convert AC to DC to either : 1) save battery power by allowing you to plug into the mains or 2) to charge a battery in the device. The design of power supplies where AC is converted into DC does take frequency into account. Even though 60 Hz converts a little more easily to DC than 50 Hz does, there's enough tolerance in most small appliances and electronic gadgets that you can ignore frequency. However, if you also need to change the voltage (because the voltage of your device is different from the mains power voltage), you cannot use a switching-type converter. You must use the heavier iron-core transformer. If in doubt, consult a reputable electrical goods dealer.
If your device won't operate with a different frequency (powerful motors and all clocks), there is really nothing you can do to change it. Unlike voltage, frequency cannot easily be converted. Foreign embassies may have to use huge generators to provide current compatible with equipment from home.
Japan is a special case. East Japan (eg Tokyo) uses 50 Hz and west Japan (eg Osaka) uses 60 Hz. Equipment made for the Japanese market may have a switch to select 50 Hz or 60 Hz.
Here is another
The higher voltage of 250 VAC means there will be less current for a given load, and therefore less power loss along a given length of wire having a given diameter. The length and diameter of the copper wire determine its resistance. The power loss is equal to the current squared, multiplied by the resistance. So, less current means less power loss.
The lower voltage of the USA means less efficiency, but greater safety. It is less likely to receive a fatal electrocution from the lower voltage under the same conditions.
The 50 Hz vs the 60 Hz makes little difference. The machinery making the 50 Hz rotates a little slower and may need slightly less maintenance. Products based on 60 Hz could weigh slightly less due to smaller transformer cores and motor armatures needed, but that doesn't really happen because most products are designed to run on either frequency.
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