I'd use a 50/50 mix of the two. I did that when I had to do an emergency waterchange with seachem once. A bucket of my regular IO became available shortly after and I ended up mixing the two for the rest of the seachem bucket. It actually worked out quite nicely as the two complemented each other (IO sucks for mg, seachem is quite good). However, I had had some issues with just seachem on its own.
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