You can but Acrylic expands a bit when it heats up so leave a bit of room or it could snap your glass. It might not be as durable as glass but is possible most overflows are plexy and glued in.
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150 Gal system 3'x3' 400W M/H, Bekett skimmer, Dart return,1/4 HP Chiller
180 Gal Drop tank, LED lights, Bubble master 250 skimmer,Hammerhead on a closed loop, Speed wave return.
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