I ran them in line . I had the rowaphos in the first one flowing into the one with carbon and then into my sump. This way you only have to use one pump. Ran the phosban 3/4 full of carbon. Water was very clear and didn't have to clean glass as often. Found it worked quite well. I only have about 80 to 85 gallon system. Also it should say on the container of carbon how much to use per gallon.
Chris
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