Hypo salinity, lower your SG slowly over a few days, research what the lowest SG lions can tolerate, each species may be different so be very carefull. I'd avoid copper itself it can be VERY hard on fish, I've used cuprimine by SeaChem and had good luck with it, it's ionically different than copper and apparently it's much easier on the fishes internal organs.
Fresh water parasites can't survive in Salt water and Salt water parasites can't survive in fresh water. IMO use a good Marine buffer as well so your pH doesn't go all over the place.
Doug
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