I would like to introduce a theory. (Could be wrong , but hey, you never know)
Could worms try to spawn? i had this happen once in my 108 Gal., and one worm started waiving its tail spraying white goo (sperm).
After that they all have gone like creasy doing the same. Water was like a milk, however cleared up fast, if that happened to your tank at night you might have missed the show but end up with a lot of toxic material in the tank so everything started to suffocate slowly. In small tank this could get to a point of no return very quickly. What do you think? I agree about doing small water changes more often rather then big one, this shocks everything even when al live stock is doing OK.
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