I've run tanks as small as 2.5g and as large as our current BB 120g skimmerless. As long as the fish load is low, you don't over feed, keep non-invasive macroalgae to consume nutrients, and you do weekly maintenance all should be well. Have been running our skimmerless BB 120g for well over a year with no nitrate.
Also, as with any reef, make sure you keep an eye on alkalinity, calcium and magnesium levels to help your corals grow.
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