I had a couple of 66 gallon Hagen tanks (48.25" x 16.25" x 20.25")... one that I bought brand new 5-6 years ago (still using it now) and one that was at least a few years old when I acquired it. Both tanks had no center brace and I believe we made from 3/8" plate glass. IMHO, you'll be fine. Both tanks did bow slightly when filled, but nothing significant.
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