It is best not to ,some european Zeo users ,inject ozone in very small dosages in their skimmer & that is in large tanks ,in small tanks the whole volume of water will get exposed to it that way & will defeat the whole purpose of using these additives to promote extra bacterial growth.
Specialy a UV filter in line on your return pump (which is how most people use it)will not work with this system..
Frankly you will not need it ,I used to dose 200 mg/hr using a pinpoint ORP controller to keep Orp around 450 mv ,I can tell you since I started with Zeo 2 years ago my water is more clear compared to before when I used to dose Ozone.
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