http://www.reefs.org/library/article...tes-jorge.html
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Indeed, much literature points towards topical application as being effective, and oral administration as futile. So why do we have numerous relations of success from hobbyists, after oral administration of garlic?
Here is a possible 'out'... or two:
Mastication by a fish cannot be so thorough as to deliver a fine garlic puree to the stomach (otherwise, many gut surveys in the field would be pointless), and thus stomach acids cannot thoroughly neutralize all enzyme before some allicin is synthesized. Garlic is at that point effective against at least gastrointestinal parasites and infections.
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Although there may not be any real conclusive scientific data ....yet, the anecdotal evidence with regards to feeding fish allicin complex to rid them of internal parasites appears to be quite strong.
Pablo's take on all of this:
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It helps to get rid of the intestinal worms and parasites on the fish. Some claim they got rid of ich by using Thera A formula, but I have experienced mixed results. It definitely helps. You can feed your fish with this formula all the time since there is no medication involved.
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Keep in mind that some of the 'marine' species in the tank shown in the link below are 7 years old, and have been eating food containing garlic on a daily basis for that entire 7 years.
http://forums.spectrumfishfood.com/viewtopic.php?t=66
While I can't comment on the safety factor involving other fish foods on the market, the garlic used in New Life Spectrum is very safe, even if fed daily, exclusively, over many years.
Does it cure marine ich? Perhaps not, but I wouldn't be too quick to dismiss its use entirely.