No, manually dosing only, and needs to be shaken first. I put in a cap full in my tank (100g) about every 2 or 3 days. When you first start, you have to dose more. And if I see any signs of cyano, I double the dosage for a week or two.

Here are the instructions. But I never shut off my skimmer,... no need to. I haven't refrigerated, but they do recommend it for longevity. I stock up once a year on boxing day.
http://brightwellaquatics.com/produc...robacter7t.php

I dosed it as per the instructions, minus the 4 hours of no skimmer each time. I dosed for 2 weeks straight everyday, and now, I just manually dose once a week.