It all boils down to whether or not you are running a shallow sand bed (less than 2") or deep sand bed (4-6"). For a SSB, you want more coarse sand that you can siphon if necessary. The Seaflor is great for this and allows sand sifting fish to accept it.
For a deep sand bed, you want to use Sugar size or oolite sand. You do not want any sand sifting fish in this setup. Some Nassarius snails are great in this case to mix up the top layer of sand. It does settle down when the bacteria colonizes and weighs it down. Still, in a high flow area, it will have a tendancy to blow around.
I ran a DSB in my 75G with very good results. Only problem is my 75 is fairly heavy stocked and ended up with some Red Slime. It is very hard to siphon anything out without making a mess. So, with my new 180G setup, I went with 2" of Seaflor Select so siphoning can easily be done if necessary and be able to keep some sand sifters. I also have a remote DSB plumbed into my system to use the benefits of that and if any problems arise with it, I can easily take it offline and not have any ill affects on my display tank.
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